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KMID : 0376219780150020345
Chonnam Medical Journal
1978 Volume.15 No. 2 p.345 ~ p.348
Effect of succinylcholine on the intra-ocular pressure

Abstract
Effect of succinylcholine on the intra-ocular pressure was assessed in 29 surgical patients in whom the intra-ocular pressure following intravenous administration of succinylcholine was measured after pretreatment of thiopental in dose to induce the loss of eye-lid reflex. The followings were the results.
1. Thiopental; showed significant lowering effect on the intra-ocular pressure.
2. A small dose(0.5mg/kg) of succinylcholine; given immediately after thiopental, restored the intra.-ocular pressure to preanesthetic level.
3. A large dose( 1.0-2.0mg/kg) of succinylcholine, administered immediately after thiopental, sustained the intra-ocular pressure below preanesthetic level.
4. Tracheal intubation caused a rise of the intra-ocular pressure above preanesthetic, level, more significantly than that of succinylcholine.
5. Succinylcholine, in a large dose, showed the depressing effect on elevation of the intra-oular pcressure induced by tracheal intubation.
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